Adenosine Deaminase, Serum

Adenosine Deaminase (ADA), Serum

What it is

The Adenosine Deaminase (ADA) Serum test measures the level of ADA enzyme in the blood. ADA is an enzyme involved in purine metabolism and plays a role in immune system function. Elevated ADA levels are often associated with certain infections, immune-related conditions, and cancers.

Uses

This test is primarily used to support the diagnosis of tuberculosis, especially when ADA levels are compared in different body fluids. It is also useful in monitoring some cancers, liver disease, and immune system disorders.

Symptoms That May Lead to the Test

Doctors may recommend the ADA Serum test for patients with prolonged fever, persistent cough, unexplained weight loss, night sweats, fatigue, enlarged lymph nodes, or symptoms suggestive of tuberculosis or chronic infections.

Abnormal Results

High ADA levels: May indicate tuberculosis, certain cancers like lymphoma, chronic infections, liver disease, or autoimmune disorders.

Low ADA levels: Usually less significant but may be seen in some cases of immune deficiency.

Risks

The test is a routine blood test with minimal risks. Possible side effects include mild pain, bruising, or bleeding at the puncture site, and rarely dizziness or infection.