CA 19-9, Cancer Marker, Serum
What it is
The CA 19-9 test measures the level of carbohydrate antigen 19-9 in the blood. It is a type of tumor marker mainly associated with cancers of the digestive system, especially pancreatic cancer. While not specific enough for screening the general population, it is useful for monitoring cancer treatment and progression.
Uses
The CA 19-9 blood test is commonly used to monitor treatment response in patients with pancreatic cancer, evaluate recurrence after surgery or therapy, and sometimes assess other cancers such as bile duct, gallbladder, liver, and stomach cancers. It may also be used alongside imaging tests for better diagnosis and follow-up.
Symptoms That May Lead to the Test
Doctors may recommend this test if you have unexplained abdominal pain, jaundice (yellowing of skin and eyes), unexplained weight loss, loss of appetite, nausea, or a strong family history of gastrointestinal cancers.
Abnormal Results
High CA 19-9: Often associated with pancreatic cancer, bile duct cancer, gallbladder cancer, liver cancer, or gastrointestinal cancers. Elevated levels may also occur in benign conditions such as gallstones, pancreatitis, liver cirrhosis, or bile duct obstruction.
Normal or Low CA 19-9: Suggests no significant increase in tumor marker levels, but does not completely rule out cancer, especially in early stages.
Risks
The CA 19-9 test is a standard blood test with minimal risks. Possible side effects include mild pain, bruising, or bleeding at the puncture site, and rarely dizziness or infection.



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