ESTRADIOL (E2), SERUM

Estradiol (E2), Serum

What it is

The Estradiol (E2), Serum test measures the amount of estradiol, the primary form of estrogen, in the blood. Estradiol is a key sex hormone responsible for the development and regulation of the female reproductive system, menstrual cycle, and secondary sexual characteristics. It is also present in males at lower levels, contributing to bone health and hormonal balance.

Uses

This test is used to assess ovarian function, evaluate menstrual irregularities, monitor fertility treatments, and help diagnose conditions like polycystic ovary syndrome (PCOS), premature ovarian failure, or menopause. In men, it may be used to investigate infertility, gynecomastia, or hormone-secreting tumors. It is also valuable in monitoring hormone replacement therapy and certain cancers (e.g., ovarian or testicular tumors).

Symptoms That May Lead to the Test

Doctors may recommend this test if you experience irregular or absent periods, infertility, hot flashes, unexplained weight changes, abnormal hair growth, or symptoms of hormonal imbalanc