Absolute Cd3, Cd4, Cd8 Count, Whole Blood

Absolute CD3, CD4, CD8 Count, Whole Blood

What it is

The Absolute CD3, CD4, CD8 Count test uses flow cytometry to measure the number of T-lymphocyte subsets in the blood. CD3 represents total T cells, CD4 indicates helper T cells, and CD8 represents cytotoxic T cells. These immune cells play a vital role in protecting the body against infections and regulating immune function.

Uses

This test is widely used to monitor immune function, particularly in people with HIV/AIDS. It helps diagnose and evaluate immunodeficiency disorders, track immune recovery after organ transplantation, chemotherapy, or other immunosuppressive therapies, and assess autoimmune conditions.

Symptoms That May Lead to the Test

Doctors may order this test if a patient experiences recurrent or frequent infections, is undergoing HIV monitoring, shows signs of immune suppression, or has autoimmune-related symptoms. It is also essential in evaluating patients before and after transplantation.

Abnormal Results

Low CD4 Count: Suggestive of HIV/AIDS, severe immune suppression, or bone marrow failure.

High CD8 Count: May indicate viral infections, chronic inflammation, or autoimmune diseases.

Abnormal CD4/CD8 Ratio: Indicates immune imbalance and is a key marker in HIV disease progression.

Risks

The test is performed using a routine blood sample. Risks are minimal and may include slight pain, bruising, or bleeding at the puncture site, and in rare cases, dizziness or infection.