Total IgE (Immunoglobulin E), Serum
What it is
The Total IgE (Immunoglobulin E) test measures the overall level of IgE antibodies in the blood. IgE is an antibody produced by the immune system in response to allergens, and high levels are often associated with allergies, asthma, or certain immune conditions.
Uses
This test is primarily used to evaluate allergic diseases such as asthma, hay fever, eczema, and food allergies. It also helps in monitoring parasitic infections and some rare immune disorders. In some cases, it is used alongside specific IgE testing to identify exact allergens.
Symptoms That May Lead to the Test
Doctors may order this test if you have frequent sneezing, runny nose, itching, skin rashes, wheezing, shortness of breath, or chronic cough. It is also advised for patients with unexplained allergic reactions or suspected parasitic infections.
Abnormal Results
High IgE Levels: May indicate allergic conditions, asthma, atopic dermatitis (eczema), parasitic infections, or rarely immune disorders and certain cancers such as IgE myeloma.
Low or Normal IgE Levels: Suggests no significant allergic response, though allergies cannot be completely ruled out as some people may have normal IgE despite symptoms.
Risks
The Total IgE test is a simple blood test with minimal risks. Possible side effects include mild pain, bruising, or bleeding at the puncture site, and rarely dizziness or infection.



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